This repo includes source codes for reproducing analysis in our study.
The source codes for producing each figure are organized in separated Jupyter notebook. All required data and scripts are included in the folder.
For more detail, please read our paper titled "Machine learning modeling of protein-intrinsic features predicts tractability of targeted protein degradation" or visit the shiny app at http://mapd.cistrome.org/.
Wubing Zhang, Shourya S. Roy Burman, Jiaye Chen, Katherine A. Donovan, Yang Cao, Boning Zhang, Zexian Zeng, Yi Zhang, Dian Li, Eric S. Fischer, Collin Tokheim, X. Shirley Liu (2021). "Machine learning modeling of protein-intrinsic features predicts tractability of targeted protein degradation" Biorxiv