diff --git a/src/dependencies.jl b/src/dependencies.jl
index a6c8519e..aaf1afff 100644
--- a/src/dependencies.jl
+++ b/src/dependencies.jl
@@ -16,12 +16,17 @@ function get_local_clone(
     return local_path
 end
 
-function get_project_deps(project_file::AbstractString; include_jll::Bool=false)
+function get_project_deps(project_file::AbstractString; include_jll::Bool, open_prs_for_extras::ExtrasType)
     project_deps = Set{DepInfo}()
     dep_section = Dict{DepInfo,String}()
     project = TOML.parsefile(project_file)
 
-    for section in ["deps", "weakdeps"]
+    sections = if open_prs_for_extras isa NoExtras
+        ["deps", "weakdeps"]
+    else
+        ["deps", "weakdeps", "extras"]
+    end
+    for section in sections
         if haskey(project, section)
             deps = project[section]
             add_compat_section!(project)
@@ -38,7 +43,12 @@ function get_project_deps(project_file::AbstractString; include_jll::Bool=false)
                     compat_entry = DepInfo(package)
                     dep_entry = convert(String, strip(get(compat, name, "")))
 
-                    if !isempty(dep_entry)
+                    if isempty(dep_entry)
+                        # Ignore dependencies in `[extras]` without a compat entry if `open_prs_for_extras` is `IfExistingCompatExtras()`
+                        if section == "extras" && open_prs_for_extras isa IfExistingCompatExtras
+                            continue
+                        end
+                    else
                         compat_entry.version_spec = semver_spec(dep_entry)
                         compat_entry.version_verbatim = dep_entry
                     end
diff --git a/src/main.jl b/src/main.jl
index 8a1e9a16..ae05b2d7 100644
--- a/src/main.jl
+++ b/src/main.jl
@@ -15,6 +15,7 @@
         cc_user=false,
         bump_version=false,
         include_yanked=false,
+        open_prs_for_extras::CompatHelper.ExtrasType=CompatHelper.IfExistingCompatExtras(),
     )
 
 Main entry point for the package.
@@ -37,6 +38,15 @@ Main entry point for the package.
 - `cc_user=false`: CC the user on the pull requests
 - `bump_version=false`: When set to true, the version in Project.toml will be bumped if a pull request is made. Minor bump if >= 1.0, or patch bump if < 1.0
 - `include_yanked=false`: When set to true, yanked versions will be included when calculating what the latest version of a package is
+- `open_prs_for_extras::CompatHelper.ExtrasType=CompatHelper.IfExistingCompatExtras()`: How to handle dependencies in `[extras]`.
+  Can be `CompatHelper.IfExistingCompatExtras()` (only open a pull request for a dependency in `[extras]` if a compat entry for it exists),
+  `CompatHelper.AllExtras()` (open pull requests for all dependencies in `[extras]`),
+  or `CompatHelper.NoExtras()` (do not open pull requests for dependencies in `[extras]`).
+
+!!! note
+    The `open_prs_for_extras` keyword argument and
+    the `CompatHelper.AllExtras`, `CompatHelper.IfExistingCompatExtras`, `CompatHelper.NoExtras`, and `CompatHelper.ExtrasType` types
+    are considered experimental (not public API) and may be changed or removed in a non-breaking release.
 """
 function main(
     env::AbstractDict=ENV, ci_cfg::CIService=auto_detect_ci_service(; env=env); kwargs...
@@ -51,7 +61,7 @@ function main(
 
     for subdir in options.subdirs
         project_file = @mock joinpath(local_clone_path, subdir, "Project.toml")
-        deps, dep_sections = get_project_deps(project_file; include_jll=options.include_jll)
+        deps, dep_sections = get_project_deps(project_file; include_jll=options.include_jll, open_prs_for_extras=options.open_prs_for_extras)
 
         populate_dep_versions_from_reg!(deps; options)
 
diff --git a/src/utilities/types.jl b/src/utilities/types.jl
index 523a1972..61aa4818 100644
--- a/src/utilities/types.jl
+++ b/src/utilities/types.jl
@@ -26,6 +26,11 @@ mutable struct DepInfo
     end
 end
 
+abstract type ExtrasType end
+struct AllExtras <: ExtrasType end
+struct IfExistingCompatExtras <: ExtrasType end
+struct NoExtras <: ExtrasType end
+
 function Base.in(p::Package, s::Set{DepInfo})
     for i in s
         if i.package == p
@@ -56,4 +61,5 @@ Base.@kwdef struct Options
     cc_user::Bool = false
     bump_version::Bool = false
     include_yanked::Bool = false
+    open_prs_for_extras::ExtrasType = IfExistingCompatExtras()
 end
diff --git a/test/dependencies.jl b/test/dependencies.jl
index 257c1bb9..db60d202 100644
--- a/test/dependencies.jl
+++ b/test/dependencies.jl
@@ -14,24 +14,82 @@ end
 @testset "get_project_deps" begin
     project = joinpath(@__DIR__, "deps", "Project.toml")
 
-    deps, dep_section = CompatHelper.get_project_deps(project; include_jll=true)
+    deps, dep_section = CompatHelper.get_project_deps(project; include_jll=true, open_prs_for_extras = AllExtras())
+    @test length(deps) == 6
+    @test issetequal([dep.package.name for dep in deps], ["Baz", "Bex_jll", "Car", "Foobar_jll", "LinearAlgebra", "Skix"])
+    @test issetequal(keys(dep_section), deps)
+    for (k, s) in pairs(dep_section)
+        if k.package.name ∈ ["Bex_jll", "Skix"]
+            @test s == "weakdeps"
+        elseif k.package.name ∈ ["Baz", "Car"]
+            @test s == "extras"
+        else # k.package.name ∈ ["Foobar_jll", "LinearAlgebra"]
+            @test s == "deps"
+        end
+    end
+
+    deps, dep_section = CompatHelper.get_project_deps(project; include_jll=false, open_prs_for_extras = AllExtras())
+    @test length(deps) == 4
+    @test issetequal([dep.package.name for dep in deps], ["Baz", "Car", "LinearAlgebra", "Skix"])
+    @test issetequal(keys(dep_section), deps)
+    for (k, s) in pairs(dep_section)
+        if k.package.name == "Skix"
+            @test s == "weakdeps"
+        elseif k.package.name ∈ ["Baz", "Car"]
+            @test s == "extras"
+        else # k.package.name == "LinearAlgebra"
+            @test s == "deps"
+        end
+    end
+
+    deps, dep_section = CompatHelper.get_project_deps(project; include_jll=true, open_prs_for_extras = IfExistingCompatExtras())
     @test length(deps) == 5
+    @test issetequal([dep.package.name for dep in deps], ["Baz", "Bex_jll", "Foobar_jll", "LinearAlgebra", "Skix"])
     @test issetequal(keys(dep_section), deps)
     for (k, s) in pairs(dep_section)
         if k.package.name ∈ ["Bex_jll", "Skix"]
             @test s == "weakdeps"
-        else
+        elseif k.package.name == "Baz"
+            @test s == "extras"
+        else # k.package.name ∈ ["Foobar_jll", "LinearAlgebra"]
             @test s == "deps"
         end
     end
 
-    deps, dep_section = CompatHelper.get_project_deps(project; include_jll=false)
+    deps, dep_section = CompatHelper.get_project_deps(project; include_jll=false, open_prs_for_extras = IfExistingCompatExtras())
     @test length(deps) == 3
+    @test issetequal([dep.package.name for dep in deps], ["Baz", "LinearAlgebra", "Skix"])
     @test issetequal(keys(dep_section), deps)
     for (k, s) in pairs(dep_section)
         if k.package.name == "Skix"
             @test s == "weakdeps"
-        else
+        elseif k.package.name == "Baz"
+            @test s == "extras"
+        else # k.package.name == "LinearAlgebra"
+            @test s == "deps"
+        end
+    end
+
+    deps, dep_section = CompatHelper.get_project_deps(project; include_jll=true, open_prs_for_extras = NoExtras())
+    @test length(deps) == 4
+    @test issetequal([dep.package.name for dep in deps], ["Bex_jll", "Foobar_jll", "LinearAlgebra", "Skix"])
+    @test issetequal(keys(dep_section), deps)
+    for (k, s) in pairs(dep_section)
+        if k.package.name ∈ ["Bex_jll", "Skix"]
+            @test s == "weakdeps"
+        else # k.package.name ∈ ["Foobar_jll", "LinearAlgebra"]
+            @test s == "deps"
+        end
+    end
+
+    deps, dep_section = CompatHelper.get_project_deps(project; include_jll=false, open_prs_for_extras = NoExtras())
+    @test length(deps) == 2
+    @test issetequal([dep.package.name for dep in deps], ["LinearAlgebra", "Skix"])
+    @test issetequal(keys(dep_section), deps)
+    for (k, s) in pairs(dep_section)
+        if k.package.name == "Skix"
+            @test s == "weakdeps"
+        else # k.package.name == "LinearAlgebra"
             @test s == "deps"
         end
     end
@@ -142,13 +200,17 @@ end
     project_file = joinpath(pkgdir(CompatHelper), "Project.toml")
 
     # Just for this test, we hardcode this list
-    unregistered_stdlibs = ["Base64", "Dates", "Pkg", "UUIDs"]
+    unregistered_stdlibs = ["Base64", "Dates", "Pkg", "Random", "Test", "UUIDs"]
 
     @test ispath(project_file)
     @test isfile(project_file)
     for use_existing_registries in [true, false]
         options = CompatHelper.Options(; use_existing_registries)
-        deps, _ = CompatHelper.get_project_deps(project_file)
+        deps, _ = CompatHelper.get_project_deps(
+            project_file;
+            include_jll=false,
+            open_prs_for_extras=IfExistingCompatExtras(),
+        )
         for dep in deps
             @test dep.latest_version === nothing
         end
diff --git a/test/deps/Project.toml b/test/deps/Project.toml
index ebe0127d..06263055 100644
--- a/test/deps/Project.toml
+++ b/test/deps/Project.toml
@@ -4,7 +4,6 @@ version = "1.0.0"
 
 [deps]
 Foobar_jll = "6ca821de-e512-569d-89d9-0b16ce691416"
-Baz = "ea10d353-3f73-51f8-a26c-33c1cb351aa5"
 LinearAlgebra = "37e2e46d-f89d-539d-b4ee-838fcccc9c8e"
 
 [weakdeps]
@@ -14,6 +13,10 @@ Skix = "3db6da90-6ed3-11ee-0779-f549c8e3e90d"
 [extensions]
 Ext = ["Bex_jll", "Skix"]
 
+[extras]
+Baz = "ea10d353-3f73-51f8-a26c-33c1cb351aa5"
+Car = "0add4187-88db-462b-bf06-da4bec59fd54"
+
 [compat]
 Foobar_jll = "1"
 Baz = "1"
diff --git a/test/runtests.jl b/test/runtests.jl
index 793cf395..8b2dc4f9 100644
--- a/test/runtests.jl
+++ b/test/runtests.jl
@@ -1,7 +1,7 @@
 using Aqua
 using Base64
 using CompatHelper
-using CompatHelper: DepInfo, EntryType
+using CompatHelper: DepInfo, EntryType, AllExtras, IfExistingCompatExtras, NoExtras
 using Dates
 using GitForge
 using GitForge: GitForge, GitHub, GitLab